Five researchers (Orkin, Sankaran, Bauer, Thein, Tisdale) won the 2026 Warren Alpert Foundation prize for work identifying BCL11A as a regulator of the fetal-to-adult hemoglobin switch, which led to Casgevy. Doudna said Casgevy is approved in 39 countries, over 90 percent of US sickle cell patients qualify for reimbursement coverage, and more than 500 patients globally have begun treatment.
Gene Editing Monthly
CRISPR, base and prime editing: clinical trial readouts, regulatory decisions and the research that moves the field.
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Oct 6 · 1 of 1 shownThis issue holds a single item, a report from the 2026 Warren Alpert Foundation Symposium honoring five scientists behind the research that led to Casgevy, the first CRISPR medicine. It is worth reading for Doudna's figures on Casgevy's global reach and the challenges she says remain.
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